Orange County Health Care Agency (OCHCA) has been notified of its first probable monkeypox virus case. Probable cases are those who test positive for orthopoxvirus DNA by polymerase chain reaction (PCR) assay. Probable cases will be sent to the Centers for Disease Control and Prevention (CDC) for monkeypox virus confirmation. Probable cases are managed as monkeypox virus cases while awaiting laboratory confirmation. More info...